Pentamidine is a diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Pentamidine isetionate is toxic and personnel should be adequately protected during handling and administration—consult product literature. Medicinal forms There can be variation in the licensing of different medicines containing the same drug.Pentamidine treatment (in cases where wheezing occurs, the Pentamidine aerosolization will be terminated and a small volume nebulizer treatment of one (1) unit dose bronchodilator will be administered, then the Pentamidine therapy will be completed). Special Considera-tions The practitioner must utilize proper safety attire and equipment which.Exposure of health care workers to pentamidine isethionate J. R. Beach, M. Campbell and D. J. Andrews Institute of Occupational Health, University of Birmingham and Departments of Occupational Health and Cliniral Biochemistry, University Hospital Trust, Birmingham, UK Pentamidine isethionate is currently used for the prophylaxis and treatment of.
Pentamidine isethionate was approved by the FDA on June 15, 1989, for use in the treatment of Pneumocystic jiroveci (formerly Pneumocystis carinii) pneumonia (PCP) in AIDS patients. Although pentamidine may be administered intramuscularly (IM) or intravenously (IV) for the treatment of PCP, only the IV route is currently recommended.
Pentamidine(Pentam) generic is an antimicrobial agent, prescribed for pneumonia and for treating leishmaniasis, yeast infections. This medication proved to be an effective antibiotic in children.
Pentamidine, when used with other antibiotics, was found to be particularly effective against two of the three pathogens which the WHO has identified as having the most critical priority for.
Pentamidine: Pentamidine can be used instead of suramin for a first stage treatment of trypanosomiasis. It is medication with a very slow rate of diffusion across biological membranes and it only treats the T.B.G. form of African sleeping sickness in the first stage. It could be injected or inhaled by the patient.
CLP Classification, Labelling and Packaging The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals.
Pentamidine is an antifungal medication that fights infections caused by fungus. Pentamidine is used to prevent and treat pneumonia caused by Pneumocystis jiroveci (carinii). Pentamidine may also be used for purposes not listed in this medication guide.
Pentamidine and amphotericin were as effective as meglumine. Use of itraconazole and other therapies (pentoxifylline, allopurinol, or interferon-gamma) was controversial, and numbers of patients in some studies were insufficient for statistical analysis. Meglumine may be the drug of choice in the treatment of ML, as it offers similar cure rates.
US Custom Essay Service at Your Door Step!!! The global essay writing service delivering pro-quality help and secure experience to customers worldwide.
Pentamidine isethionate Drug Entry Pentamidine. Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Define pentamidine. pentamidine synonyms, pentamidine pronunciation, pentamidine translation, English dictionary definition of pentamidine. n a drug used to treat protozoal infections, esp pneumonia caused by Pneumocystis carinii in patients with AIDS n. an antiprotozoal substance, C19H24N4O2.
Precautionary Practices of Respiratory Therapists and Other Health-Care Practitioners Who Administer Aerosolized Medications Rebecca J Tsai, PhD Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio.
The uptake of (3 H)pentamidine into wild-type and drug-resistant strains of Leishmania mexicana was compared.Uptake was carrier mediated. Pentamidine-resistant parasites showed cross-resistance to other toxic diamidine derivatives. A substantial decrease in accumulation of the drug accompanied the resistance phenotype, although the apparent affinity for pentamidine by its carrier was not.
Evidence-based information on pentamidine isetionate from hundreds of trustworthy sources for health and social care.
Consumer information about the medication PENTAMIDINE ISETHIONATE - INHALATION (Nebupent), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug PENTAMIDINE ISETHIONATE - INHALATION.